Optimizing Adhesive Bonding to Caries Affected Dentin: A Comprehensive Systematic Review and Meta-Analysis of Dental Adhesive Strategies following Chemo-Mechanical Caries Removal

Although there are several studies that have evaluated the bond strength of various adhesives to healthy dentin and caries-affected after traditional caries removal, objective this systematic review aimed assess (CAD) chemo-mechanical removal (CMCR) treatment. The adhered PROSPERO protocol registration followed PRISMA guidelines. research question focused on bonding effectiveness dental CAD employing method. PubMed, TRIP database, Scopus were searched, with last search conducted in February 2023. Two reviewers independently screened articles, resulting 30 articles for full-text analysis out 434 retrieved from databases. Twelve eligible included review. etch-and-rinse (ER) self-etch (SE) adhesive systems was assessed following CMCR treatment CAD. SE exhibited higher compared ER systems. Meta-analysis indicated achieved self-etching remained consistent, regardless agent (Carisolv or Papacarie) used dentin. findings suggest show favorable specific used. These results support use minimally invasive dentistry techniques at preserving tooth structure, particular.